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A multi-panel structural biology figure on protein-ligand binding, arranged as three connected panels. The large left panel (A) shows a full protein cartoon ribbon in a soft blue-to-teal gradient with alpha-helices and beta-sheets clearly distinguished, a small-molecule ligand rendered as colored sticks nestled inside the active-site pocket shown as a translucent gray surface. A dashed callout box zooms into panel (B): the binding-site close-up with key residues as labeled sticks (Asp189, Ser195, His57, Gly216, Trp215) and dashed yellow hydrogen bonds annotated with distances (2.8 A, 3.1 A, 2.9 A). The lower-right panel (C) plots binding affinity, an isothermal titration or saturation curve, x-axis Ligand concentration (uM), y-axis Fraction bound, with Kd = 0.42 uM and a labeled fit line. Clean publication-quality rendering, tidy layout, legible sans-serif labels, panel letters bold, neutral white background.
